Red bumps on the inner thighs that are very painful are most likely folliculitis, or sebaceous cysts with infection. For mild infections, oral antimicrobials are usually sufficient to achieve better clinical relief. Commonly used antibacterial drugs, mainly for staphylococcus aureus and other positive cocci selected. Such as first-generation cephalosporins, macrolides and penicillin antibacterial drugs. Commonly used are amoxicillin, clavulanate potassium, roxithromycin, and cefadroxil. If the pain is more obvious and oral drugs are ineffective, intravenous drugs such as cefradine and penicillin can also be considered. When the local redness and swelling are obvious, magnesium sulfate, ichthyol ointment or Ruyi Jinhuang San can also be used externally for wet compresses. If a pus embolism is formed, a sterile hollow needle or blade can also be applied to pick out its internal embolism head and promote the discharge of its internal secretion. If the red bump has generated an abscess, it should be incised and drained in a timely manner to remove the pus, and bacterial culture and drug sensitivity test should be done according to the pus to guide the clinical use of drugs. At the same time with hydrogen peroxide rinse clean, remove its necrotic material. If the granulation tissue is fresh, you can also consider giving a second-stage suture or applying befoji to promote the growth of granulation and achieve wound healing.