Acne is a common dermatologic disease, and its main causes include inflammatory factors, immune system imbalance, androgens, and over-proliferation of Propionibacterium acnes. 1. Inflammatory factors: In the process of acne formation, inflammation plays a crucial role in the whole process. 2. Imbalance of the immune system: Various parts of the immune system are involved in the inflammatory response to acne, affecting the skin barrier function. 3. Androgenic effects: Higher levels of androgens in the body trigger the sebaceous glands to become hyperactive and secrete large amounts of oil, leading to the formation of acne. 4. Excessive proliferation of Propionibacterium acnes: This triggers an inflammatory reaction around the hair follicles, stimulating the appearance of localized pustules and papules. In addition, the formation of acne is also affected by psychological and genetic factors. When the symptoms are mild, patients should actively adjust their lifestyle, dietary habits and mindset, and pay attention to hygiene. If there is no improvement, the patient should go to a specialized hospital in time to clarify the specific cause of the disease and follow the doctor’s instructions for treatment.