Coccidioidomycosis is an acute inflammation of the oral mucosa caused by a variety of cocci, and the clinical treatment mainly includes local treatment, systemic anti-infection treatment and supportive therapy. 1. Local treatment: you can choose to contain drugs to achieve the effect of astringent pain, sterilization, the treatment of coccidioidomycosis stomatitis, generally common drugs are chlorhexidine mouthwash, povidone-iodine mouthwash. 2. Systemic anti-infective treatment: you can inject antibiotics and take antibiotics, effectively inhibit the growth of germs, can achieve the role of treatment, generally use cefuroxime, metronidazole. 3. supportive treatment: by taking vitamin tablets can also effectively achieve the role of supportive treatment, can resist the disease, generally can choose vitamin B, vitamin C. Coccidioidomycosis is mainly these methods above, if you do not receive regular treatment, it will lead to mucosal pain, unable to eat normally, it is recommended to seek medical attention in time. The use of medications is subject to medical advice.