Leukocytes 14.5 x 10^9/L is a significant increase in white blood cells for an adult. Whether leukocyte 14.5×10^9/L is serious or not depends on the cause of the elevated leukocytes and the patient’s own symptoms, for example, leukocyte 14.5×10^9/L in adults with perianal pain and infection. Leukocytes 14.5×10^9/L is likely to be caused by perianal infection, usually after anorectal surgery treatment, such as giving surgical treatment or the application of antibacterial drug treatment, perianal infection control, symptomatic relief, the white blood cells will gradually drop to normal, there is no obvious harm to the human body. However, if the white blood cells are 14.5×10^9/L, the patient also has anemia, bleeding and other symptoms, routine blood tests found that hemoglobin decreased, platelet count decreased. It is likely to be acute leukemia caused by leukocytes 14.5 × 10^9 / L, the consequences will be very serious, and need to do bone marrow aspiration examination in a timely manner, after the diagnosis is given in a timely manner chemotherapy.