Lung cancer patients’ inability to sleep may be caused by physiological factors such as nervousness and excessive pressure, or considered to be caused by disease pain and neurasthenia. 1. Physiological factors: if lung cancer patients have long-term nervous tension and excessive pressure, it may affect the sleep quality and make them unable to sleep. This kind of situation is normal, and most patients may have this kind of situation, so there is no need to worry too much. Maintaining a positive and optimistic attitude and releasing pressure appropriately can relieve the pain. 2. Disease pain: Lung cancer patients often suffer from chest pain, cough, dyspnea, headache, nausea, vomiting, etc., accompanied by local redness, swelling, pain, tachycardia and other symptoms. If patients feel sick, they may not be able to sleep. 3. Neurasthenia: neurasthenia is caused by long-term tension and high-pressure state. Patients may have symptoms such as slow reaction, memory loss, difficulty in falling asleep and poor quality of sleep. There are many reasons why patients with lung cancer can not sleep, and it is suggested that patients should find out the causes in time.