Significant hard lumps in the nipple, not excluding those caused by dilation of the milk ducts, or occupying lesions in the milk ducts, such as medial papillomas. The cause of occurrence is related to recurrent local inflammatory irritation, or the patient has a previous history of recurrent nipple discharge, as well as a history of mastopexy. If necessary, a combination of ductoscopy, color ultrasound of the breast and other relevant tests are required, and in severe cases, surgical treatment is possible. The cause of breast disease is endocrine disorders, and the habits and lifestyle of daily life, there is a certain correlation. Staying up late, eating irregularly or overeating can affect changes in hormone levels in the body, which can also lead to breast disease. These include lesions in the milk ducts, dilation of the milk ducts, or occupying lesions in the breast glands. Many patients require surgical treatment when necessary.