Differential diagnosis of epilepsy

  Syncope is due to a sudden onset of transient cerebral insufficiency of blood supply, causing inhibition of the brainstem reticular upward activating system, resulting in a transient state of loss of consciousness. Loss of consciousness for more than 10-20 seconds can occur as convulsions or hypoxic epileptiform seizures, manifested as tonic spasms or even urinary incontinence, which is known as convulsive syncope.  The distinction between syncope and epilepsy is generally made from the following aspects: 1. Onset triggers: Syncope mostly has obvious triggers, such as sudden rising, severe pain, emotional excitement, excessive coughing, laughing, breath-holding, etc. Epilepsy often has a sudden onset without any triggers.  2, position: syncope occurs mostly in the standing position, partly in the sitting position, and rarely in the lying position. In contrast, epilepsy is not necessarily. Syncopal seizures are usually slow to fall, while epileptic collapses occur suddenly.  3. Precursory symptoms: Syncope is often associated with dizziness, sweating, nausea, weakness, pallor, abdominal discomfort, etc. The aura of epilepsy is mostly epigastric discomfort, fear, flushing, and a sense of unreality. Phantom smell or sense of déjà vu is more specific in patients with partial seizures.  4. Seizure performance: pale face, lower blood pressure, slow and weak pulse, and less frequent convulsions during syncopal seizures. In contrast, seizures with cyanosis, increased pulse, and twitching of the limbs may be accompanied by biting of the tongue and urinary incontinence.  5. Post-ictal performance: recovery from syncopal seizures is faster, and there are no obvious symptoms after the seizure. Slow recovery after generalized tonic-clonic seizures of epilepsy, often with a period of confusion, drowsiness and headache. Although the epileptic’s disoriented seizure recovers quickly, there is no fall, and it is easy to distinguish from syncope.  6, EEG: syncopal seizures are mainly slow waves with normal interictal periods. Characteristic epileptic discharges are seen in both seizures and interictal periods.