Elderly woman with slightly red papules in the elbow fossa and N fossa, dry without exudation, with intense itching, aggravated after bathing and at night, affecting sleep, usually not sweating easily and not sleeping well. Cold season, dry skin, itching and rashes are not uncommon in the elderly, usually treated by nourishing blood and moistening dryness to dispel wind and relieve itching, with emolliency, the effect is not certain. However, the author screened the drugs and chose Agaricus blazei to nourish the dryness of the skin and Huang Lian and Scutellaria baicalensis to remove the redness and heat of the rash as the core prescription, which quickly relieved the pain and obtained the same effect when the condition recurred later, supporting the clinical value of this group of prescriptions.