The treatment of glomerular microscopic lesions is with immunosuppressant therapy, the most commonly used method is to apply 0.8-1mg of hormone per day according to the body weight, and after 2-3 months of high-dose treatment, the dosage is slowly reduced, and the total course of treatment is in the range of 1.5-2 years, and in this type of pathology, the effect of hormone therapy alone is better. For patients who are resistant or insensitive to hormones, if they are treated with hormones for 2 months and still do not see any improvement, it is recommended to switch to tacrolimus or cyclosporine. Tacrolimus and cyclosporine also need to be calculated according to body weight, and the blood concentration should be checked once a month to adjust the dose in time to prevent the concentration from being too high to cause tumors, and to prevent the concentration from being too low, which is ineffective against the disease.