The causes of thick nails are physiological factors and pathological factors, pathological factors such as hereditary palmoplantar keratosis, nail fungal disease, nail psoriasis, lichen planus, etc., and their treatments include medication and physical therapy. 1. Physiological factors: generally with age, the body’s metabolism slows down, there will be toenail thickening and bulging, which is a normal phenomenon, you can soak your feet, and then use scissors to cut thin. 2. Pathological factors Hereditary palmoplantar keratosis: can also appear thickening of the toenails, treatment, can be used externally urea cream, vitamin A acid ointment, salicylic acid ointment, etc., sealing package softening keratin treatment. Nail fungal disease: mainly caused by fungal infection, the treatment can first use a knife or nail file to remove as much as possible the diseased nail, and then use 30% glacial acetic acid solution to soak until the growth of new nails; can also be used 40% urea cream sealing package, so that the diseased nails soften detachment; topical antifungal drugs, such as 8% cyclopiazepine, etc., antifungal treatment; the condition of the heavier, oral antifungal treatment, such as itraconazole and so on. Nail psoriasis: this disease can lead to nail thickening, peeling, etc. It can be treated with topical captopanol betamethasone cream or combined laser treatment. Lichen planus: this disease can lead to thickening of nails. For treatment, topical glucocorticoid closure therapy, such as mometasone furoate ointment, etc.; topical retinoic acid drugs, such as retinoic acid ointment, etc., to exfoliate the keratin; if there is severe itching, oral antihistamines can be used to treat the condition, such as loratadine, cetirizine, etc.; if necessary, physiotherapy can be taken. It is recommended that patients with thickened nails go to a regular hospital in time, follow the doctor’s instructions for treatment, do not self-medication.