Vulvar skin suddenly grow a rough skin consider vulvar eczema, vulvar sclerosing moss, psoriasis, etc., the main drug treatment, according to the cause of the disease to choose the appropriate drugs. 1. vulvar eczema: vulvar eczema is an inflammatory skin disease that occurs in the vulva area, in the acute stage, you can apply hydrocortisone cream, dexamethasone cream, after the condition is stabilized, you can use tacrolimus ointment, pimecrolimus ointment, and if there is a combination of infections, you can use erythromycin ointment, mupirocin ointment and so on. 2. Vulvar sclerosing moss: a disease that mainly develops in the perianal skin of the vulva, with parchment-like or cigarette paper-like thickening, hyperplasia, or moss-like changes in the skin. You can apply hydrocortisone, fluoride easy, testosterone propionate, etc., itching symptoms can be oral diclofenac tadalafil, cetirizine and so on. 3. Psoriasis: This is a chronic scaly skin disease caused by the interaction of many factors, and can apply tazarotene gel, adapalene gel and so on. Those with severe itching can apply glucocorticoid creams such as tretinoin cream and dexamethasone cream. Vulvar skin suddenly grow a piece of rough skin should be timely consultation, for the cause of the medicine, all the above drugs should be used under the guidance of the doctor.