Breast nodules do not usually develop after the insertion of the Mannion IUD, and breast nodules may be related to other factors. The Mannuelle Ring is a contraceptive ring that is used clinically for contraception as well as for idiopathic menorrhagia (i.e., menorrhagia that is not caused by organic pathology). The Ring contains progesterone, which acts on the woman’s uterine lining. Only a small amount of the hormone enters the bloodstream, and basically has no effect on the breast tissue. Nodules in the breast need to be considered as a result of other causes. Breast nodules can be categorized into physiological nodules and pathological nodules. Physiologic nodules are worse before the onset of menstruation, but will gradually subside afterward and do not require special treatment. If the nodules are pathological, they need to be treated with radiotherapy, chemotherapy or surgery. If the patient finds a nodule in the breast at the same time of placing Mannuelle Ring, he/she should go to the hospital in time and follow the doctor’s instructions strictly for treatment.