Whether pleural thickening is scary or not mainly requires determining the specific cause of its thickening; thickening caused by simple inflammation and local irritation is not scary; thickening caused by neoplastic lesions is a more scary condition. 1. Inflammation or physical and chemical stimulation can cause pleural thickening, most of the thickening will be reduced after the causative factors are relieved, and some of them will have slight adhesion, which is not a terrible condition, and a large part of them will not have obvious symptoms. 2. The appearance of pleural metastasis or mesothelioma can also lead to pleural thickening, generally the thickening is more obvious, the thickness is uneven, accompanied by respiratory limitation, most of the cases will be a decline in physical condition, which is a horrible condition, and need to be treated in time. Once significant pleural thickening is detected, prompt medical attention is required. After diagnosing the condition, standardized treatment will be carried out under the guidance of clinicians.