Urine protein 2 + indicates that there is protein leakage in the urine, if it is physiological leakage, usually no harm, if long-term leakage, it will affect kidney function, may lead to edema, infection, thrombosis and so on. Under normal circumstances, the urine routine urine protein negative, 24-hour urine protein quantitative <150mg / d. Positive urine protein can be seen in the short-term large amount of protein, fever and other physiological conditions, at this time to adjust the lifestyle can be generally improved, there is no great harm. If the urine protein is positive for a long time, we need to consider that it is caused by the disease, most often seen in kidney disease such as nephrotic syndrome. Prolonged leakage of large amounts of protein, serum albumin will drop, may cause body edema, increased risk of infection, induced thrombosis, and in severe cases can lead to acute renal failure. In addition, non-glomerular proteinuria includes overflow proteinuria and histiocytic proteinuria, such as multiple myeloma, which often manifests as bone pain and fever, and can be life-threatening in severe cases. When you find positive urine protein, you should go to the hospital in time and follow the doctor's instructions for diagnosis and treatment.