Friends and family gatherings, it is inevitable to drink a couple of, no wine is not a seat, no wine is not happy well! However, the wine drink too much, but also to pay the price. As we all know, we drink wine, are degrees, the degree, representing the content of alcohol, that is, the content of ethanol. A lot of clinical data shows that ethanol will not only cause harm to the brain, resulting in memory loss, time and trouble, but also damage our heart, gastrointestinal and other organs, alcohol on our body is one of the most damaging organs is the liver. Alcoholic liver disease (ALD) is a liver disease caused by heavy alcohol consumption. Initially, it usually manifests itself as fatty deposits in liver cells, which is usually referred to as alcoholic fatty liver, which can then develop into alcoholic hepatitis, alcoholic liver fibrosis and alcoholic cirrhosis, and can induce extensive liver cell necrosis and even liver failure in severe alcohol abuse. Some cirrhotic patients who continue to drink alcohol can further become liver cancer. In western countries, alcoholic liver disease is one of the main causes of cirrhosis. Alcoholic liver has become the second leading cause of cirrhosis after viral hepatitis in China. Research results show that more than 80% of heavy drinkers have some degree of fatty liver, of which 10% to 35% can develop into alcoholic hepatitis and 10% to 20% can develop into liver cirrhosis. Patients who drink a lot of alcohol over a long period of time, drinking 80 to 160g of alcohol per day, have a liver that is 57 times more dangerous than normal. According to statistics, more people die in alcohol than in seawater every year. The metabolism of alcohol is basically done by the liver. 20% of the alcohol drunk is absorbed in the stomach, the rest enters the small intestine, 80% of which is absorbed in the small intestine. About 90% to 98% of the absorbed alcohol passes through the blood circulation and eventually enters the liver, where it is oxidized by ethanol dehydrogenase to acetaldehyde, then further oxidized by aldehyde dehydrogenase to acetic acid finally generating carbon dioxide and water through the tricarboxylic acid cycle. However, there is a limit to this metabolic capacity. As the saying goes, “It takes more than one day to freeze three feet of ice.” Alcoholic liver is not a day or two, it is a chronic damage, in general, we say that alcoholic liver is the result of two conditions, one is the long-term drinking, a large amount of alcohol consumption. If you drink on one meal and drink on the next, alcoholic fatty liver will occur for more than 5 years in a row, and then continue with alcoholic hepatitis – alcoholic cirrhosis. Drinking alcohol is more likely to cause liver damage when: Drinking on an empty stomach is more likely to cause liver damage than drinking with a meal. Women are more sensitive to alcohol-mediated hepatotoxicity. Lack of vitamin A or decreased vitamin E levels may also exacerbate liver damage. Obesity or excess body mass can increase the risk of progression of alcoholic liver disease. Alcohol consumption on the basis of hepatitis virus infection or concomitant HBV or HCV infection on the basis of alcoholic liver disease can accelerate the development and progression of liver disease. Also drinking alcohol after taking cold medicines containing paracetamol can worsen liver damage. People who drink less definitely do not bring the same degree of damage to the liver as people who drink more, and people who drink slowly do not bring the same degree of damage to the liver as people who drink hard. Why do fast drinkers and fast drinkers tend to get drunk! This is the reason. How can we estimate the degree of damage to our liver from alcohol? Here is a conversion formula is: ethanol amount (g) conversion formula = drinking volume (m1) × ethanol content (%) × 0.8. In other words, you drink a pound (500 m1) of liquor, multiply by the alcohol content, and then multiply by a factor of 0.8 to know how many grams of ethanol you drank down. Long-term alcohol consumption is the amount of converted ethanol ≥ 40 g/day for men and ≥ 20 g/day for women, more than 5 years. Heavy drinking is defined as 80 g/day of equivalent ethanol in 2 weeks. So, here, remind those who have a long-term habit of drinking alcohol for more than 5 years, and at the same time, each time they drink, the amount they drink greatly exceeds the daily drinking amount recommended by the Chinese Nutrition Association, they must hurry to the hospital to check your liver. Once alcoholic liver is detected, can it be cured? The first stage is the alcoholic fatty liver stage, which generally does not require treatment and can be recovered after you stop drinking. In the second stage, alcoholic hepatitis, liver function can be restored within a month after quitting drinking and undergoing liver-protective treatment, but this usually requires oral liver-protective drugs and hospitalization. The third stage, cirrhosis stage. Once you enter this stage, it will be more difficult to recover. There is a possibility of reversing compensated cirrhosis, but some patients are difficult to reverse, and serious patients need artificial liver or even liver transplantation treatment. Therefore, it is crucial to stop drinking as early as possible. What should alcoholic liver patients do to protect their liver? What are the considerations in life? The first one is to stop drinking, because many patients with alcoholic liver have alcohol dependence, that is, they feel uncomfortable without drinking and have alcohol addiction. Alcohol addiction in turn aggravates alcoholism, forming a cycle of nausea. Alcoholic liver patients should pay attention to the following aspects of their diet: 1. A diet high in energy, protein and vitamin-rich is needed to correct coexisting malnutrition. 2. The intake of fat should be strictly limited. The calories from fat should be 15-20% of the total calories. After not drinking, should also strengthen exercise, fatty liver patients suitable exercise is persistent, low moderate intensity, longer aerobic exercise, such as collapsing boxing and stepping on the back of the foot are good exercises to protect the liver, with the role of liver conditioning, dredging the liver and bile, after doing, the forehead slightly sweating. Of course, in the alcoholic hepatitis stage of liver function is obviously abnormal friends, should avoid doing strenuous exercise. In short, alcoholic liver is drinking out, healthy people should drink less, alcoholic liver patients should quit drinking, regulate diet, more exercise, so that our liver, a chemical plant more efficient and environmentally friendly.