(Disclaimer: This article is for scientific purposes only. In order to protect the patient’s privacy, the relevant information in the following content has been processed) Abstract: The patient’s fatigue worsened after activity, anorexia of greasy food, accompanied by a cough and lack of sputum, and was diagnosed with non-alcoholic fatty liver disease through relevant examinations after consulting the hospital. The patient was discharged from the hospital with relief of symptoms after being given hepatoprotective and enzyme-lowering treatments. Non-alcoholic fatty liver disease is a typical “rich man’s disease”, which is caused by non-alcoholic factors, and is characterized by hepatocellular steatosis and accumulation of fat in the liver, accompanied by abnormalities of lipid metabolism and abnormalities of glucose intolerance. Basic information] Female, 38 years old [Type of disease] Non-alcoholic fatty liver disease [Hospital] Liaoning Provincial People’s Hospital [Time of consultation] November 2018 [Treatment plan] Drug treatment + symptomatic treatment (liver protection + lipid-lowering treatment) [Treatment cycle] Hospitalization for 7 days, outpatient follow-up after 2 weeks [Treatment effect] Patient’s symptoms have been improved I. Initial interview Patient with obesity build, came to the clinic for 3 months and 1 week for worsening due to lack of energy. The patient was obese and had been suffering from fatigue for 3 months, which had worsened for 1 week. More than 3 months ago, the patient was self-conscious of fatigue without obvious triggers, aggravated after activities, anorexia of greasy food, cough, no sputum, consulted in the nearby hospitals, liver function tests were abnormal, and further came to our hospital, outpatient laboratory tests were positive for Hepatitis B surface antigen, liver function was abnormal, outpatient clinic diagnosis of chronic viral hepatitis B, the examination of the Hepatitis B virus is negative, the ultrasensitive Hepatitis B virus is negative, liver, gallbladder and spleen ultrasound suggests fatty liver. Liver function was rechecked and returned 160U/L of alanine aminotransferase, further examination and treatment were recommended, and the patient agreed to be admitted to the ward. After admission, the patient was admitted to the hospital with routine secondary care, bed rest, low-fat and low-sugar diet, and relevant examinations were completed. At present, the patient was considered to have chronic liver injury, non-alcoholic fatty liver disease, and Hepatitis B virus carrier, but other diseases were excluded from further examination. Combined with the history, physical examination and laboratory tests, hepatitis B virus quantitatively negative, except chronic hepatitis B; the patient has no history of alcohol consumption, except alcoholic hepatitis; no history of medication, except medication hepatitis; thyroid function is normal, except hyperthyroidism liver disease; autoimmune hepatitis spectrum negative, except autoimmune liver disease, the laboratory test of EB virus antibody is negative, except EB viral hepatitis; cytomegalovirus IgG positive. IgM weakly positive, but blood routine did not see lymphocytes and monocytosis, no heterogeneous lymphocytes, no fever, no lymph node swelling, etc., the diagnosis of cytomegalovirus hepatitis is insufficient; combined with the patient’s metabolic syndrome such as elevated blood lipids, glucose tolerance abnormality, obesity, etc., and insulin resistance, and the transaminases and transpeptidases are elevated, the diagnosis of non-alcoholic steatohepatitis was determined. The patient was given compound diisopropylamine dichloroacetate injection at rest and levocanidin oral solution orally to reduce blood lipids. After 7 days of symptomatic treatment of hepatoprotection and lipid-lowering, the effect was remarkable. The patient’s symptoms such as fatigue and greasiness improved, and the abnormal indexes of review were returned, and the blood lipids were completely normalized, blood glucose returned to normal, and the liver function test was obviously improved, with the following symptoms: alanine aminotransferase: 25.4U/L, azelaic aminotransferase: 40.7U/L, alkaline phosphatase: 63U/L, transketolase: 54U/L, and total bilirubin: 23.1U/L, and total bilirubin: 23.1U/L. Bilirubin: 23.1umol/L, the condition improved and discharge was granted. After discharge, the patient was discharged from the hospital with instructions to continue to take medication to protect the liver, oral compound diisopropylamine dichloroacetate tablets and levocanidin oral solution, and to continue to pay attention to the dietary structure, to increase the exercise exercise, and to repeat the examination in the outpatient clinic after 2 weeks. Precautions: We are glad that the patient’s symptoms have been improved after treatment, but we still remind the patient to pay attention to some matters in daily life: 1, the patient’s liver function was basically normal when he was discharged from the hospital, and he continued to take oral diisopropylamine dichloroacetate tablets, to improve the metabolism of liver fat, and levocarnitine oral solution to reduce the blood lipids, because the function of the liver cells has not yet been restored, so we should avoid the application of statin lipid-lowering drugs, which can easily cause drug-induced hepatitis. Cause drug hepatitis; 2, the diet of fatty liver patients is very important, must adjust the dietary structure, it is recommended that high protein, low fat and low carbohydrate diet, high protein diet can reduce intrahepatic fat. At the same time, increase the amount of exercise to accelerate fat metabolism, however, the exercise should not be too strenuous, and must stop drinking; 3, hepatitis B virus quantification needs to be regularly rechecked, hepatitis B virus can be re-replicated or re-activated, usually pay attention to rest, and reduce the unnecessary use of drugs to avoid aggravating the burden on the liver. V. Personal perception For the patient’s case, it can be seen that with the improvement of living standard and the change of diet structure, the incidence of fatty liver is increasing year by year, and, the age of discovery is getting younger and younger. In addition, non-alcoholic fatty liver disease is different from alcoholic liver disease, alcoholic liver disease can be improved after quitting alcohol, while non-alcoholic liver disease is mainly more concurrent with insulin resistance or diabetes mellitus, lipid metabolism abnormality and other problems, which will produce more serious consequences if they are not emphasized and controlled by long-term medication. Fatty liver disease can be completely reversed if the cause is removed, diet is improved, exercise is strengthened, and medication is used appropriately. However, if the patient is allowed to progress to cirrhosis or liver cancer, the prognosis is poor, so early intervention is crucial, and clinicians need to strengthen the education.