Causes of alcohol addiction

Alcohol addiction is also called alcohol dependence, drinking behavior is very common in people’s daily life, adults do not drink alcohol in their lifetime, which accounts for only 5%, in addition to complete abstinence from alcohol, any degree of alcohol consumption is considered to be the potential population of alcohol dependence. According to the WHO in 2004, there are 2 billion drinkers in the world, of which an estimated 140 million are alcohol-dependent. Alcohol is the most widely used addictive substance in the world, permeating daily life, socio-economic and cultural activities. Alcohol consumption has been a long-standing and common habit and social custom. However, long-term excessive alcohol consumption can lead to alcohol abuse and alcohol addiction, accompanied by a variety of mental, physical and social damage, bringing serious adverse effects to individuals, their families and society. Etiology: Molecular abnormalities in biological cell membranes are the essence of alcohol addiction; all alcoholics have chronic alcohol tolerance, and the reason why they remain sober despite abnormally high blood ethanol concentrations may be a function of ethanol-adapted membrane mechanisms in the nervous system. Human cellular biofilms (including the central nervous system) that are frequently exposed to alcohol, i.e., the body’s tissue fluids are constantly exposed to a certain concentration of alcohol, become biologically dependent on the nervous system, and the individual develops tolerance to alcohol. The process is: alcohol by affecting the function of transcellular membrane signaling proteins, through the voltage-dependent channels, neurotransmitters and hormone receptors and other target organs, and intracellular Ubiquitin triphosphate – binding protein or ion channels, second messenger proteins and protein hormone enzymes coupled, and then affect the transcription of genetic genes, the level of expression and cellular metabolism. Resulting in adaptive cellular tolerance to alcohol. In terms of the central nervous system as a whole, this is manifested in abnormal behavioral responses to alcohol and alcohol addiction, which creates a physiological dependence on alcohol in the body.