A minimum interval of one month is usually required between vaccines. Since most vaccines take one month to complete detoxification, if other vaccines are given at the same time during the detoxification period, the immune response of the other vaccine will be affected and the immune effect will be weakened. Most of the vaccinations can be postponed but are not recommended to be advanced. Therefore, it is important to follow medical advice strictly when vaccinating and not to try to advance vaccination on your own. The timing of vaccination is based on long-term clinical drug detoxification time and drug efficacy. For example, the timing of vaccination for hepatitis B vaccine is 0, 1 and 6 months, i.e. within 24 hours after birth, 1 month of age and 6 months of age, etc. The timing and doses of vaccination are different for each vaccine.