Gallbladder adenomyosis is a proliferation of glands and muscles in the wall of the gallbladder, and a limited size of 15mm x 6mm is not particularly serious. Gallbladder adenomyosis itself is a benign tumor, the current limited size of 15mm x 6mm should be considered for surgical treatment, but it is not particularly serious, the condition can be controlled after surgery, usually does not cause complications, and most of the patients’ symptoms are not obvious. Moreover, the prognosis of gallbladder adenomyosis after surgical treatment is good, generally will not affect the life expectancy of patients, and will not shorten the survival time. The general recommendation for adenomyosis is laparoscopic cholecystectomy, which is a more thorough and less risky procedure that can completely eradicate the disease. Early diagnosis and treatment of adenomyosis can effectively prevent the risk of malignant lesions. Regular follow-ups should be conducted after the surgery and professional treatment should be carried out according to the later diagnosis to prevent postoperative recurrence.