Coughing when waking up and coughing before going to bed needs to be considered as a respiratory disease, which commonly includes acute episodes of chronic pharyngitis, rhinitis, sinusitis, and acute rhinitis and sinusitis, including reflux esophagitis complicated by reflux pharyngitis. Due to the inflammatory reaction, there is a large amount of airway secretion exudation, including esophageal secretion, stomach acid, etc., when lying down, it is easy to reflux to the pharynx, stimulate the back wall of the pharynx, coughing symptoms. At night the human sympathetic nerves will also be relatively excited, and the secretion of the glands in the airway will be vigorous, and the glandular secretion will increase. When waking up, the more secretions accumulated during the night will also irritate the wall of the pharynx, aggravating the symptoms of coughing.