Gallbladder polyps are actually not terrible, because most of them are benign, and even if they are larger than 1cm in diameter, the cancer rate is less than 1%. However, once the gallbladder polyp becomes cancerous, especially if it invades the muscle layer or exceeds the muscle layer, the prognosis is extremely poor, and it has the notorious name of “king of cancers”, even if the polyp is less than 10mm, it may be malignant. Minimally invasive biliary polyp removal is in line with precision medicine: 1, for suspected cancerous lesions 2, laparoscopic technology was originally intended to be a diagnostic tool, and even today it has developed into minimally invasive surgery, but still retains its function of direct vision and taking specimens for diagnosis. 3, although polyp cancer is a small probability event, we can’t know 100% when a certain individual polyp has undergone a qualitative change. The intraoperative examination of the specimen can be clear. 4.Minimally invasive is very little impact on the human body, the polyps are removed immediately and sent to the fast frozen section, and then decide whether to bile preservation or bile cutting, which is accurate and does not add trouble and treatment costs, so it can be said “all in one go” 5.B ultrasound follow-up is very convenient and accurate. 6.In the past 5 years, there were 200-300 cases of polyps biliary surgery in our center each year, and on average, 1~3 cases of carcinoma in situ and 5 cases of invasion to muscle layer were found each year. Most of the gallbladders have avoided the fate of being sacrificed for nothing just because of the possibility of cancer. Except for cholesterol crystals or small polyps of 3-5 mm, all of these gallbladders are healthy and working for the body.