Betahistine Mesylate can be taken with Roaccutane. Betahistine mesylate works by increasing cerebral and peripheral blood flow and improving microcirculation. Roxithromycin is an antibacterial drug. The two can be taken together. It is recommended to use them under the guidance of a doctor. Betahistine mesylate is generally used for cerebral arteriosclerosis, insufficient blood supply caused by cerebral ischemic disease, inner ear vertigo and so on. It mainly has a vasodilatory effect on blood vessels, which can increase cerebral blood flow and peripheral blood flow and improve microcirculation. Cannot be combined with histamine drugs. Contraindicated in children, women during pregnancy. Common adverse reactions include nausea, vomiting, and occasionally rash. Roxithromycin is an antimicrobial drug, can be used to treat sinusitis, otitis media, acute bronchitis, pharyngitis caused by sensitive bacteria. It cannot be used together with ergotamine and dihydroergotamine. It is contraindicated for those who are allergic to erythromycin or other macrolides. Adverse reactions include nausea, vomiting, abdominal pain and diarrhea. In general, betahistine mesylate and roxithromycin can be taken together will not have too much effect. The use of drugs must follow the doctor’s instructions, not blindly use their own drugs, so as not to cause adverse consequences.