The decision to operate depends on the location of the nodule, the size of the nodule, and the benignity or malignancy of the nodule. For example, if a nodule occurs in the thyroid gland, it is usually seen as a nodular goiter, simple goiter and thyroid adenoma, or thyroid cancer. Simple goiter or nodular goiter can be treated conservatively when the nodule is small, for example, less than 1 cm or less than 2 cm. If the nodule is large, has symptoms of pressure or causes hoarseness, then surgery is required to remove it. In the case of thyroid adenoma, surgery is usually recommended if the diagnosis is clear. In the case of thyroid cancer, surgery is also necessary to remove both thyroid glands and the lymph nodes on the side of the tumor.