Serum creatine kinase isoenzyme clinically refers mainly to creatine kinase CK-MB, and its normal value varies depending on the laboratory and assay method, and is usually less than 0.05 U/L or between 0 and 18 U/L.
Creatine kinase CK-MB is mainly found in the myocardium and is a specific indicator for the diagnosis of myocardial injury. The level of CK-MB is commonly detected clinically by electrophoresis and enzyme rate method (37°C), and its normal range is usually less than 0.05 U/L when detected by electrophoresis, while its normal range is 0~18 U/L when detected by enzyme rate method (37°C).
Creatine kinase CK-MB is mostly used to assess the current extent of myocardial necrosis. If CK-MB is elevated, it suggests that there may be myocardial injuries, such as acute infarction, myocardial injury, pericarditis, etc.; it may also suggest that there are skeletal muscle injuries, such as polymyositis, muscular dystrophy, etc. The low CK-MB index has no clinical significance in the diagnosis and identification of the disease.
When the creatine kinase CK-MB is found to be high, it is recommended to consult a doctor in time to avoid delaying the condition.