People who are allergic to cow’s milk protein can get the pneumonia vaccine, there is no necessary connection between the two. People who are allergic to cow’s milk are rarely allergic to the 13-valent pneumonia vaccine because the pneumonia vaccine is inactivated prior to vaccination, and inactivated proteins do not, or very rarely, cause allergic reactions in humans. In addition, the vaccine’s adjuvant or the production process does not generally use cow’s milk. To be on the safe side, it is usually necessary to observe the vaccination site for about one hour after the pneumonia vaccination. If there is no skin rash, itching, or difficulty breathing, an allergic reaction is not expected.