There are more than 10 variant strains of Neocoronavirus at present, and the more common ones include Beta, Delta, and Omicron. 1. Beta: A mutated strain of the New Coronavirus is capable of mutating the spiny protein, causing an immune escape phenomenon, i.e., antibodies produced by previous infection with the virus or antibodies produced by vaccination may be weakened. 2. Delta: This virus is characterized by a short incubation period, high viral load, rapid transmission, greater susceptibility to developing critical illness and a long nucleic acid conversion time. 3. Omicron: this mutated virus is characterized by fast transmission, strong transmission ability and stealth, prone to produce more mutations, which may cause the risk of secondary infection. All of these viruses are hazardous and must be actively treated with standardized isolation and require good nursing care.