Blood creatinine is the result of kidney function test, high blood creatinine is not necessarily suffering from uremia, it may also be a normal phenomenon caused by excessive exercise, it may also be caused by renal insufficiency, if the patient’s blood creatinine is more than 707 μmol/L, it is considered to be uremia. 1. Excessive exercise: If the patient has a lot of exercise before the kidney function test, it will cause the patient to have high blood creatinine, which is a normal phenomenon, so it is not uremia. 2. Renal insufficiency: renal insufficiency is mainly caused by many factors such as acute and chronic renal diseases and extra-renal diseases. The main symptoms of patients are anorexia, diarrhea, depression, insomnia, etc., as well as irritability, memory loss, etc. The patients’ renal function test results show high blood creatinine, and if the blood creatinine is not more than 707μmol/L, it is not uremia. 3. Uremia: Uremia belongs to the end stage of renal insufficiency, which is mainly caused by various factors such as chronic, progressive, irreversible destruction of renal units, etc. The main symptoms of patients are dyspnea, poor appetite, anemia, impaired consciousness, sensory abnormalities, dark complexion, etc. If the blood creatinine value is more than 707μmol/L, it is not uremia. If the blood creatinine value exceeds 707μmol/L, it is considered to be uremia. It is recommended that patients with elevated blood creatinine should consult a regular hospital in time and follow the doctor’s instructions for standardized treatment.