The 3 main treatment principles for atrial fibrillation are anticoagulation, ventricular rate control, and prevention and control of complications. 1. anticoagulation, anticoagulation is mainly oral medication, warfarin, dabigatranate and rivaroxaban. The most common is gastrointestinal bleeding, and the patient’s stool should be observed. 2. control the ventricular rate, the ventricular rate is best controlled below 110 beats per minute, when the patient does not have the typical symptoms of panic. 3. to prevent and control the emergence of complications, the most likely complications of atrial fibrillation large cerebral infarction, pulmonary embolism, acute myocardial infarction and lower extremity arterial occlusive disease. At this time, patients will have corresponding symptoms, such as acute dyspnea, coughing up blood, pain in the precordial region, swelling of the lower limbs, etc. Therefore, attention should be paid to the above problems in the treatment of atrial fibrillation.