Cranial repair surgery is a routine surgery in neurosurgery, and the technology has been quite mature after a long period of development. At present, the most widely used repair material for skull repair is titanium, but it is not the ideal material and there are still some problems. So what are the disadvantages of titanium alloy skull repair? In fact, we may sometimes see some patients with cranial defects using titanium alloy material to repair the skull, and after a period of time, there may be scalp tissue ablation, titanium alloy exposed, which is due to the titanium alloy and human tissue compatibility is not ideal, resulting in a rejection reaction. This is one of the disadvantages of titanium alloy repair cranial bone, in addition to titanium alloy repair cranial bone disadvantages can also have chronic pain, cutting ulcers, postoperative infection, postoperative patients sensitive to hot and cold reactions, affect the postoperative CT nuclear magnetic examination and so on. PEEK material has good biocompatibility, complex shaping, excellent mechanical properties, good protective properties, and high postoperative comfort, and is gradually becoming the latest trend in cranial repair materials. The latest trend in materials for skull repair.