The method of relieving the pain of otitis externa is based on medication, and the commonly used drugs are non-steroidal anti-inflammatory drugs, such as diclofenac sodium and ibuprofen. It should be noted that the causes of otitis externa are different, and the treatment should be based on different causes to choose the appropriate drugs. If the otitis externa is caused by water in the ear, unreasonable ear digging and colds, you can use ofloxacin ear drops for ear baths after removing the secretions from the ear. At the same time, oral or intravenous antibiotics can be given to fight inflammation. Commonly used drugs are cephalosporins and beta-lactam antibiotics. If the symptoms of otitis externa are severe and edema is obvious. Dexamethasone can be used to reduce swelling. In the course of treatment, medicines are used to keep the ears dry and clean. The pain caused by this disease, if relatively mild, may not require special treatment, but the pain is severe need to be vigilant, such as necrotizing otitis externa, adenoid cystic carcinoma, etc., if necessary, the use of non-steroidal anti-inflammatory drugs, such as ibuprofen, diclofenac sodium. Patients with otitis externa should go to regular hospitals in a timely manner to clarify the cause of the disease and standardize the use of medication and treatment under the guidance of specialists.