Erectile dysfunction in men can be classified as psychological erectile dysfunction, organic erectile dysfunction and mixed erectile dysfunction according to the cause, involving various problems in the brain, hormones, emotions, nerves, muscles and blood vessels, and its treatment also includes a variety of techniques: First-line therapy: inhibition of phosphodiesterase 5 activity can block cGMP hydrolysis and increase its concentration, inducing penile vascular and cavernous sinus smooth muscle relaxation, which can induce erection by increasing blood flow to the penile arteries. Phosphodiesterase 5 is a widely distributed enzyme in penile cavernous tissue that hydrolyzes cyclic ornithine phosphate (cGMP). Current highly selective PDE5 inhibitors include sildenafil, tadalafil and vardenafil. The second line of treatment: vacuum negative pressure device therapy, where a negative pressure ring is placed at the root of the penis to stop blood flow back, and negative pressure acts on the penile corpus cavernosum to attract blood into the penis, resulting in passive erection. Penile corpus cavernosum drug injection therapy, through prostaglandin E1, poppies, phentolamine and other vasodilating drugs injected into the penile corpus cavernosum, through the local vasodilating effect to induce an erection. However, the dosage of drugs used and the method of drug injection must be determined under the guidance of a physician to avoid serious comorbidities. Third line of treatment: Surgical treatment with penile erectile device implantation is the treatment of choice for severe patients who have failed to respond to the first and second line of treatment. There are two types of erectors to choose from, a flexable (semi-rigid) and an expandable erector (two, or three piece set). Most patients prefer the three-piece expandable erector because it provides a more “natural” erection, but has the disadvantage of the possibility of mechanical failure and other complications. The two-piece prosthesis has a lower incidence of mechanical failure and is simpler to implant and can be surgically replaced again. In addition, you can also change the poor lifestyle through general treatment, psychotherapy and other means to prevent and control high-risk factors, such as increasing exercise, weight loss and disable drugs that can cause ED, active treatment of diabetes, hypertension, the original law of the disease. Psychotherapy is applied to patients with obvious psychosomatic diseases, psychosexual treatment can be carried out alone or with other treatment modalities, but the efficacy is uncertain. Patients can be treated clinically with a step therapy approach, according to the severity and different etiology to choose a treatment plan.