Uremic patients can generally live 10-30 years after effective treatment. If there are no serious comorbidities such as diabetes, coronary heart disease, cerebral infarction, etc., many patients can survive for more than 20 years, and the highest can even reach 40 years, if they strictly follow the medical advice of regular and adequate dialysis with good control of blood pressure, improvement of anemia, maintenance of electrolyte balance and strict control of diet. However, if combined with serious comorbidities such as diabetes, coronary heart disease and cerebral infarction, life expectancy will be greatly reduced. Without regular and adequate dialysis or without dialysis, patients with uremia may die at any time due to acute left heart failure, severe hyperkalemia, resulting in fatal arrhythmias, severe metabolic acidosis, etc.