Statin refers to statin lipid-lowering drugs. Elderly people over 75 years old can take statin drugs, but they should pay attention to the damage of the drugs to the liver and rhabdomyolysis. Elderly people over 75 years old are the high incidence of cardiovascular and cerebrovascular diseases, for the existence of atherosclerosis, we should actively control the blood lipid level, statins are the main drugs to reduce blood lipids, can prevent the progress of atherosclerosis, the elderly patients can take normal. Statin drugs mainly cause damage to the liver and muscle, elderly patients should regularly review liver function and kinase during the course of taking the drug to prevent liver function impairment and rhabdomyolysis. The main adverse reactions of statin drugs include stomach upset, nausea, vomiting, etc. It is forbidden for patients with allergy to drug ingredients, unexplained elevation of liver enzymes, and severe liver function impairment.