Failure of mother-to-child blockade of triple positive requires timely medical observation, regular review and active treatment. Triple positive generally refers to antibodies and antigens that appear in the human body after the hepatitis B virus infects the human body, including hepatitis B surface antigen (HBsAg), hepatitis B E antigen (HBeAg), hepatitis B core antibody (anti-HBC) three positive, when a pregnant woman’s body of the hepatitis B virus is too large in the quantitative DNA and does not take antiviral drugs correctly, there is a possibility of failure of the blockade of mother-to-child. When the blockade fails, it means that the virus already exists in the fetus and the child will be infected with hepatitis B virus after birth, then you need to consult a doctor in time for observation and regular checkups, and if the viral content is high, you need to use interferon and other drugs under the guidance of the doctor to avoid delaying the induction of liver damage to the fetus’s health and irreparable harm. Newborns infected with hepatitis B, once the active stage of hepatitis B must be actively treated, generally after regular treatment of the child’s symptoms will be significantly improved.