Oral hypoglycemic drugs are generally not recommended in pregnancy. Pregnant women are advised to carry out lifestyle intervention and appropriate exercise to lower blood glucose, and apply insulin subcutaneous injection for treatment if necessary. Women who develop diabetes during pregnancy need to adopt lifestyle intervention methods such as dietary control and appropriate exercise to control blood glucose under the guidance of a doctor. If the blood glucose still fails to reach the normal level after strict lifestyle intervention, subcutaneous injection of insulin is needed to control the blood glucose. Whether it is diabetes mellitus combined with pregnancy, or high blood glucose in pregnancy, oral hypoglycemic drugs are not recommended, and it is recommended to apply insulin subcutaneous injection treatment to control blood glucose. Pregnant women with high blood glucose should test their blood glucose regularly, eat a regular diet, avoid overeating, avoid high-sugar, high-calorie foods, and also burn calories through appropriate exercise to improve the symptoms of high blood glucose.