Acute pyelonephritis as well as acute episodes of chronic pyelonephritis require treatment with antibiotics. Non-acute exacerbations of chronic pyelonephritis require integrated nephrologic therapy. Pyelonephritis is divided into two types: acute pyelonephritis and chronic pyelonephritis. Acute pyelonephritis and chronic pyelonephritis are mostly caused by bacterial infection. At this time, antibiotics are needed for treatment, and the more commonly used ones are amoxicillin, cefixime, levofloxacin and so on. If the patient’s bladder irritation symptoms are more obvious, you can also add three gold tablets and other drugs to improve the symptoms. The treatment of chronic pyelonephritis in non-acute exacerbation is mainly the integrated treatment of chronic kidney disease, i.e., lowering the blood pressure, protecting the kidneys, and treating all kinds of complications, such as the application of erythropoietin to treat renal anemia, and nifedipine controlled-release tablets and other treatments for renal hypertension. The treatment of pyelonephritis needs to be carried out under the guidance of physicians in regular hospitals, do not take medication on your own, not to mention the gullibility of biased prescriptions and secret prescriptions.