There is no such thing as “the top ten heat-removing and detoxifying medicines”, but common heat-removing and detoxifying traditional Chinese medicines include honeysuckle, forsythia, panax quinquefolium, dandelion, etc., and proprietary Chinese medicines include Huanglian Shangqing Pill, panax quinquefolium granules, and scutellaria baicalensis oral solution. The main effect of heat-clearing and detoxifying medicines is to clear away fire, heat and toxicity. It is mainly applied to various heat and toxic diseases, such as carbuncle, sore throat, snake and insect bites, burns, scalds, cancer, and warm fever. Honeysuckle and forsythia are contraindicated for those with deficiency of spleen and stomach (spleen and stomach weak and cold) and those with deficiency of qi in sores and ulcers with clear pus; Banlangen is contraindicated for those with deficiency without actual fire and heat toxins, and is used with caution for those with deficiency of spleen and stomach; overdose of dandelion may lead to diarrhea. Huanglian Shangqing Pill has the efficacy of clearing heat, dispersing wind and relieving pain. It is used for dizziness and distention caused by internal heat and fire, swollen and painful gums, mouth and tongue sores, red and swollen throat, earache and tinnitus, outbreak of fire eye (i.e. infectious conjunctivitis, also known as red eye), dry stools, and yellow-colored urine. Its adverse reactions are not clear, and it is prohibited for people with cold spleen and stomach. Banlangen Granules has the effect of clearing heat and removing toxins, cooling blood and relieving pharynx. It is used for sore throat and dryness of mouth and throat caused by heatiness of lung and stomach; acute tonsillitis with the above symptoms. Its adverse reactions and contraindications are not clear. Blue Baicalin Oral Liquid has the effect of clearing heat and removing toxins, relieving pharyngeal swelling. It is used for acute pharyngitis, sore throat, dry throat and burning throat caused by solid heat in lung and stomach. Its adverse reactions and contraindications are not clear. Heat-clearing drugs are easy to hurt the spleen and stomach, the spleen and stomach cold people should be cautious; bitter cold drugs are easy to hurt the yin, heat disease injury to the yin, yin deficiency and fluid deficiency people should be cautious; true cold and false heat evidence is prohibited. Please consult a medical professional for specific use and compounding of drugs.