Anal canal cancer is basically incurable in the case of inguinal lymph node metastasis. The cause of anal canal cancer has not been fully clarified for the time being. It is a malignant tumor disease, and relevant studies have found that it is closely related to HPV infection, sexually transmitted diseases, smoking, autoimmune diseases and so on. Although it is said that there is a chance for anal canal cancer to be cured, such a chance of cure mainly occurs in the early stage, that is, when the tumor cells have not spread and metastasized; for anal canal cancer patients with inguinal lymph node metastasis, the tumor lesions cannot be completely removed through surgery, so naturally, it is not possible to achieve the effect of completely curing the disease. For anal canal cancer patients with inguinal lymph node metastasis, although it is basically impossible to cure the disease, radiotherapy, targeted therapy and other treatments can be used to control the disease and slow down the progress of the disease, so as to improve the prognosis of the disease. Once diagnosed with anal canal cancer, patients should actively cooperate with the treatment regardless of their condition to improve the quality of life.