Not all diabetes require lifelong insulin, diabetes is categorized into type 1 diabetes, type 2 diabetes, special type of diabetes and gestational diabetes. There are several types of diabetes: i. Type 1 diabetes mostly starts in adolescents, and the cause of the disease is related to pancreatic β-cell failure, mainly insulin deficiency, so it needs insulin treatment for the whole life. ii. Second, type 2 diabetes mellitus oral hypoglycemic drug treatment is ineffective, combined with acute and chronic complications, perioperative period, etc. also need short-term insulin therapy, a few oral hypoglycemic drugs are ineffective, the disease course of the long and thin type 2 diabetes mellitus patients, also need to play insulin for life. Third, some special types of diabetes, such as diabetes formed after repeated pancreatitis, poor pancreatic function, also need insulin treatment. Fourth, gestational diabetes requires insulin therapy during pregnancy, and specific decisions need to be made according to the recovery of blood glucose after delivery. So the need for lifelong insulin therapy is a small number of diabetic patients, the largest number of people with type 2 diabetes, oral hypoglycemic drug therapy is the main, special circumstances also need insulin therapy.