The triggering factors of leukemia in young children include long-term exposure to ionizing radiation such as radiation, exposure to certain carcinogenic chemical substances, family inheritance, etc. In addition, other blood diseases can also develop into leukemia.
1. Physical factors: large-area and large-dose exposure to ionizing radiation such as X-rays and γ-rays can lead to bone marrow suppression and decreased immunity, resulting in DNA mutation, breakage and recombination, which can lead to the occurrence of leukemia in young children.
2. Chemical factors: frequent exposure to carcinogenic chemicals such as benzene and formaldehyde can also lead to the occurrence of leukemia in young children.
3. Family genetics: children with familial genetic defects can also develop leukemia, such as children with Philadelphia chromosome mutation, where chromosome 22 is ectopic with chromosome 9, which fuses the gene BCR with the gene ABL and increases the tyrosine kinase activity, which initiates the proliferation of the cells in the absence of growth factors, and also leads to leukemia in young children.
4. Development of other blood diseases: young children with other blood diseases, such as myelodysplastic syndromes, multiple myeloma, etc. can also gradually develop leukemia.
It is recommended to go to the hospital in time to see a doctor for leukemia in young children, and then give targeted treatment or therapy after completing the examination to clarify the cause of the disease.