Currently polyether ether ketone (peek) is now the best repair material, is bionic bone, the closest to the human autologous bone repair material, without any side effects. PEEK material repair skull, its insulation, strength, hardness, elasticity, etc. are comparable with the autologous skull, is an excellent skull repair material, and can be and 3D printing technology with the perfect restoration of the anatomical structure of the skull, precise anastomosis defect area, is the best choice for patients with cranial bone repair. The number of patients with cranial defects is particularly high, and cranial defects not only harm individuals, but also affect the life of the whole family, bringing very great harm to the family. Cranial defects require cranial repair, but many patients lack knowledge of the materials used for cranial repair, and a patient recently asked: are there many side effects of titanium mesh for cranial repair? I would like to tell you that whether the mechanical equipment has a breakdown and needs to be repaired or replaced parts, certainly with the original is also different. Not to mention the human body, this is a fact that can not be changed, the only thing you can do is to continue to update the breakthroughs, reduce its side effects. Titanium mesh repair is still a lot of shortcomings, because titanium mesh belongs to the metal material, the patient is easy to be sensitive to hot and cold stimulation after surgery, easy to produce or store fluid in the subcutaneous tissue is easy to infection, the lesion may be localized discomfort or chronic pain. Such as temporal fossa, eyebrow frame and other special parts of the repair after the appearance of poor results. Nowadays, the newest type of PEEK material for cranial bone repair is a great progress compared with the conventional repair material. PEEK material is a kind of bionic bone, which can be customized in three dimensions according to the degree of cranial bone defect, and implanted into the defect area accurately.PEEK material can be highly fused with the autogenous bone, and its performance is comparable to that of the autogenous bone in the aspects of elasticity, conduciveness, hardness, and stability, etc. PEEK material can be better adapted to the autogenous bone for the children. patients, can be better adapted to the growth and development of autologous cranial bone. Patients and friends in the choice of this new material, is still relatively scarce, it is recommended to do this kind of surgery to the authority of the hospital.