Removal of the gallbladder does not normally cause hypokalemia, but may cause hypokalemia if there is early postoperative fasting or reduced potassium intake. The gallbladder is capable of storing and concentrating bile, and then excreting it when it is needed for digestion. When the gallbladder becomes diseased (stones, tumors, inflammation, etc.), the gallbladder may be removed. After removal, bile cannot be stored and has a small effect on digestion, but it does not usually cause potassium absorption and metabolism, so it does not usually cause hypokalemia. After early cholecystectomy, fasting is required because gastrointestinal function has not yet recovered from anesthesia, which may lead to insufficient potassium intake and trigger hypokalemia. If hypokalemia occurs after cholecystectomy, it is recommended to seek medical treatment in time, actively search for the cause of hypokalemia, and standardize the treatment under the guidance of physicians.