It is essential to screen newborns for inherited metabolic diseases. China expressly provides that each newborn in the formal medical unit after birth, 1 week need to undergo screening programs, including thalassemia, sericea, congenital hypothyroidism, phenylketonuria, congenital adrenocortical hyperplasia, etc., the above-mentioned diseases are stressed to early detection, early intervention, or the use of special food, drug avoidance, can maximize the prevention of disability due to disease. For example, congenital hypothyroidism, the onset is relatively insidious, and once the general edema, low ability to eat milk, or stunted growth occurs, the diagnosis may already be 1 or even 2 years old after birth. If hypothyroidism persists, it will directly affect the brain development of newborns, leading to mental or motor developmental lag, which is irreversible once the condition lasts for a long time. Therefore, early intervention is emphasized.