Plasma D-dimer 2530.0ng/mL exceeds the normal index, but whether it is serious needs to be analyzed according to the specific situation. 1. Plasma D-dimer, an important indicator of fibrinolytic activity testing, has a reference value of 0~0.256mg/L, but different hospitals and different instruments have slightly different reference standards for testing. 2. Generally speaking, it is 2~3 times higher than the reference value, counting the elevation of the index, which has important clinical significance at this time. Therefore, plasma D-2 polymer 2530.0ng/mL (i.e. 2.530mg/L) belongs to more than normal indicators, but whether it is serious or not should be analyzed by professional doctors according to the patient’s condition. 3. In general, increased plasma D-dimer can be seen in DIC, malignant tumors, pulmonary thromboembolism, deep vein thrombosis and so on. Therefore, when abnormal elevation of plasma D-dimer is detected, it should not be easily ignored and professional doctors should be sought for treatment.