Sinusitis causes cheek pain because the sinuses are located close to the cheeks, and sinus inflammation can spread to the soft tissues of the cheeks, causing local swelling and pain. Pain can be relieved by anti-inflammatory and analgesic drugs with physical therapy.1. Medication: Nasal decongestants such as ephedrine can be applied to spray the nose to reduce the swelling of the mucosa of the nasal cavity and sinus opening and improve drainage. Antibacterial and anti-inflammatory treatment should be actively pursued, and sensitive antibiotics such as penicillins and cephalosporins should be selected. The acute inflammation of the sinuses is controlled before the inflammatory response in the cheek is reduced and the pain gradually disappears. If the pain is particularly severe, oral antipyretic and analgesic drugs such as aspirin capsules and compound acetaminophen tablets can also be used for analgesic treatment; 2. Physical therapy: local ultrashort wave irradiation can be performed, which can effectively reduce the inflammatory response in the cheek and thus relieve the pain; 3. Other: saline or hypertonic saline nasal irrigation and maxillary sinus puncture irrigation can also be applied, and the cheek pain can be effectively relieved after comprehensive treatment.