Pain in the anus is considered to be a disease that occurs below the dentate glands, most commonly thrombosed external hemorrhoids as well as anal fissures. Thrombosed external hemorrhoids due to defecation stimulation hemorrhoids, thrombus surface capillary rupture, prone to anal pain, anal fissure. Due to the stool is too dry, so that the anus appear trauma produce pain. Most of the patients will be accompanied by slight bleeding symptoms. Normally, we should pay attention to local hygiene, insist on applying salt water sitz bath or potassium permanganate solution diluted after sitz bath. And, adjust the diet structure. In addition, some patients may be due to anal fistula secondary to perianal abscess, which is not timely treated and improved, and extrudes purulent secretion out. The most important treatment is to carry out the excision of anal fistula or hanging line therapy, and after the operation, change the medicine regularly. Reasonable diet, increase dietary nutrition, to high protein food, in order to promote the healing of the wound.