Parkinson’s disease is a common neurological dysfunction disease, mostly seen in the elderly, with symptoms such as involuntary tremor of the limbs at rest, muscle stiffness, slow movements and postural balance disorders, leading to varying degrees of impairment in living ability. What is wrong with Parkinson’s disease? The brain is the “Commander-in-Chief” of the human body. If there is a problem with the brain, even if our arms and legs are intact, we may not be able to move, and the brain consists of the telencephalon, mesencephalon, midbrain, cerebral bridges, and medulla oblongata, with each of these parts performing its own function. The substantia nigra in the midbrain secretes a substance called “dopamine”, which is used to coordinate and control limb movements. In Parkinson’s disease, most of the nerve cells in the substantia nigra die, resulting in a lack of dopamine, which causes the symptoms of Parkinson’s disease, i.e., tremor, rigidity, slowed movement, and abnormal posture and gait. Is Parkinson’s disease fatal? Parkinson’s disease itself is not a fatal disease and generally does not affect the patient’s life expectancy. However, if the patient does not seek timely medical treatment or refuses to be treated, the disease can seriously affect the patient’s quality of life and make them unable to take care of themselves. These elderly patients often end up dying from serious complications, such as bone fractures, pneumonia, and urinary tract infections. How is Parkinson’s disease treated? Medication: Medication is the first choice in the treatment of Parkinson’s disease. Once a patient is diagnosed with Parkinson’s disease, medication should be administered immediately. Currently, the commonly used drugs for Parkinson’s disease include: levodopa: Medopa, Xining; dopamine agonists: Tysudan extended-release tablets, Krepla, Pramipexole; catechol-oxygen-methyltransferase inhibitors: Cotan; anticholinergic drugs: Antan; amantadine: Amantadine Hydrochloride tablets; B-type monoamine oxidation inhibitors: Silegilan. Surgery: Innovative techniques are also used when medication alone does not solve the problem. Deep Brain Stimulation (DBS) is one of the most effective treatments available for severe motor symptoms in Parkinson’s disease. Electrodes are implanted in specific neural nuclei in the patient’s brain, releasing high-frequency electrical stimulation, which inhibits the electrical impulses of the neurons and diminishes their over-excitability, thus reducing the symptoms of Parkinson’s disease.