Drugs to improve cognition in Alzheimer’s disease

Alzheimer’s disease, the current drugs that can improve cognitive function are mainly in two categories: 1, acetylcholinesterase inhibitors, currently more commonly used are donepezil, carbaplatin and stigmasterol, mainly able to increase the level of acetylcholine in the brain, by inhibiting the cholinesterase hydrolysis of acetylcholine to play a role. When the acetylcholine level is increased, it can strengthen the prominent transmission and play a role in improving cognition.2. N-methyl-D-menadione receptor antagonists, mainly represented by meperidine. This drug is able to regulate glutamate activity and is indicated for patients with moderate to severe Alzheimer’s disease.3. Sometimes, brain metabolic fugitives, such as olanzapine, aniracetam, piracetam, etc., can also be used. However, the efficacy of this drug is not yet certain and is only used as a treatment when no other drugs are available.