The stages of diabetic nephropathy are as follows: 1, Phase I: that is, the hyperfiltration stage, patients show increased glomerular filtration rate and large kidneys, but no obvious pathological changes; 2, Phase II: that is, the post-exercise microalbuminuria stage, patients show positive urine microalbumin after exercise, which may turn negative after rest; 3, Phase III: that is, the early stage of diabetic nephropathy, patients show the long-term presence of microalbuminuria, glomerular The filtration rate decreases and nephrogenic hypertension may appear; 4. Stage 4: that is, the clinical stage of diabetic nephropathy, the patient’s kidney function decreases dramatically, manifested by increased albumin in urine, edema and hypertension; 5. Stage 5: that is, the end stage, also known as advanced uremia, the patient may be ineffective through conventional conservative medical treatment and requires replacement therapy.