Spleen pain may be due to spleen disease, pancreatic disease, intercostal neuritis and so on. 1. Spleen disease: It refers to the lesion of the spleen itself or diseases related to the spleen, such as splenomegaly, splenic injury, infectious diseases, etc., which will cause pain in the left upper abdomen. Splenic lesions cause the spleen to become enlarged or damaged, leading to the pulling or destruction of the surface envelope, which eventually causes pain. 2. Pancreatic diseases: for example, chronic pancreatitis. It is usually due to alcoholism, infection of the biliary system, and so on. Because the location of the pancreas is very close to the spleen, lesions in the pancreas can also lead to discomfort in the spleen. Examples include pain, flatulence, belching (hiccups), etc. 3. Intercostal neuritis: Inflammation of the intercostal nerves due to viruses, trauma, etc. is called intercostal neuritis. It causes pain in the area innervated by the intercostal nerves, causing vague pain in the spleen area. There are many causes of splenic pain, and it is recommended to seek medical attention as soon as possible for symptomatic treatment.